Mepacrine - Wikipedia
Mepacrine, also called quinacrine or by the trade names Atabrine or Atebrin, is a medication with several uses. It is related to chloroquine and mefloquine. Although formerly available from compounding pharmacies, as of August 2020 it is totally unavailable in the United States. [1]
Quinacrine: Uses, Interactions, Mechanism of Action - DrugBank …
2005年6月13日 · Quinacrine has been used as an antimalarial drug and as an antibiotic. It is used to treat giardiasis, a protozoal infection of the intestinal tract, and certain types of lupus erythematosus, an inflammatory disease that affects the joints, tendons, and other connective tissues and organs.
Quinacrine - DermNet
What is quinacrine? Quinacrine is a derivative of quinine, synthesised from the bark of the cinchona tree. It was extensively used as an antimalarial agent for millions of servicemen in the Pacific region during the 1940s.
Quinacrine | C23H30ClN3O | CID 237 - PubChem
Quinacrine has been used as an antimalarial drug and as an antibiotic. It is used to treat giardiasis, a protozoal infection of the intestinal tract, and certain types of lupus erythematosus, an inflammatory disease that affects the joints, tendons, and other connective tissues and organs.
Quinacrine dihydrochloride - DrugBank Online
An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
Quinacrine (UNII code: 81A613ZZ6X) was not nominated for inclusion on the 503B Bulks List. METHODOLOGY Background information The national medicine registers of 13 countries and regions were searched to establish the availability of quinacrine products in the United States (US) and around the world. The World Health Organization, the
Candidate drug replacements for quinacrine in cutaneous lupus ...
Quinacrine, in particular, is used as an adjuvant therapy to other antimalarials for improved control of CLE. Quinacrine is currently unavailable in the USA, which has taken away an important component of the treatment regimen of patients with CLE.
Beyond DNA binding – a review of the potential mechanisms
2019年11月10日 · Quinacrine (IUPAC name 4-N- (6-chloro-2-methoxyacridin-9-yl)-1-N,1-N-diethylpentane-1,4-diamine) is a heterocyclic three-ring compound (Figure 1A), and an acridine (Figure 1B) derivative (9-aminoacridine). It is readily available as quinacrine dihydrochloride, the dihydrochloride salt of quinacrine, for clinical use.
Quinacrine - The Winding Road from the Most Important
2023年9月20日 · Quinacrine, the main antimalarial drug during World War II, has had a chequered history that included the successful repurposing as an intrapleural sclerosant for the treatment of malignant pleural effusions, a non-surgical method of female sterilisation, and the use as an immunomodulatory drug in l …
Quinacrine: Uses, Dosage, Side Effects, FAQ - MedicinesFAQ
2023年9月19日 · Quinacrine has been used as an antimalarial drug and as an antibiotic. It is used to treat giardiasis, a protozoal infection of the intestinal tract, and certain types of lupus erythematosus, an inflammatory disease that affects the joints, tendons, and other connective tissues and organs.