Exosome (vesicle) - Wikipedia
Exosomes, ranging in size from 30 to 150 nanometers, [1] are membrane-bound extracellular vesicles (EVs) that are produced in the endosomal compartment of most eukaryotic cells. [2][3][4] In multicellular organisms, exosomes and other EVs are found in biological fluids including saliva, blood, urine and cerebrospinal fluid. [5] .
Q&A: What are exosomes, exactly? | BMC Biology | Full Text
2016年6月13日 · Exosomes are extracellular vesicles first described as such 30 years ago and since implicated in cell–cell communication and the transmission of disease states, and explored as a means of drug discovery. Yet fundamental questions about their biology remain unanswered.
The biology, function, and biomedical applications of exosomes
2020年2月7日 · Exosomes are extracellular vesicles generated by all cells and they carry nucleic acids, proteins, lipids, and metabolites. They are mediators of near and long-distance intercellular communication in health and disease and affect various aspects of cell biology.
Exosome | Definition, Size, & Function | Britannica
Exosome, nano-sized vesicle secreted from cells that contains any of various biomolecules, such as proteins or nucleic acids. Intercellular communication by exosomes plays a critical role in the regulation of physiological processes.
Exosomes: a review of biologic function, diagnostic and targeted ...
2024年7月11日 · In this review, we briefly discuss the composition of exocomes and exosome isolation. We also review the clinical applications of exosomes in cancer biology as well as strategies in exosome-mediated targeted drug delivery systems.
The biology, function, and biomedical applications of exosomes
Ectosomes are vesicles that pinch off the surface of the plasma membrane via outward budding, and include microvesicles, microparticles, and large vesicles in the size range of ~50 nm to 1 μm in diameter. Exosomes are EVs with a size range of ~40 to 160 nm (average ~100 nm) in diameter with an endosomal origin.
Exosomes: biogenesis, biologic function and clinical potential
Exosomes are nano-sized biovesicles released into surrounding body fluids upon fusion of multivesicular bodies and the plasma membrane.
Exosomes: composition, biogenesis and function - Nature
2002年8月1日 · Exosomes are small membrane vesicles of endocytic origin that are secreted by most cells in culture. Interest in exosomes has intensified after their recent description in antigen-presenting...
The exosome journey: from biogenesis to uptake and intracellular ...
2021年4月23日 · Exosomes are small extracellular vesicles secreted by all cell types playing intercellular communication roles in health and disease by transferring cellular cargoes such as functional proteins, metabolites and nucleic acids to recipient cells.
Exosomes - PubMed
2019年6月20日 · Exosomes are small, single-membrane, secreted organelles of ∼30 to ∼200 nm in diameter that have the same topology as the cell and are enriched in selected proteins, lipids, nucleic acids, and glycoconjugates.