An individual's nerve cells produce a special chemical called serotonin. It is responsible for sending signals from one nerve ...

Mirtazapine is a tetracyclic antidepressant that increases the amount of norepinephrine and serotonin in the brain through an unknown mechanism, possibly by presynaptic receptor inhibition ...

New Delhi: IQVIA has got approval from the Subject Expert Committee (SEC) functional under the Central Drug Standard Control ...

They found that SuM to dentate granule cell synapses, which co-release glutamate and GABA, exhibit distinct differences in paired-pulse ratio, Ca2+ sensitivity, presynaptic receptor modulation, and ...

Journal of Nuclear Medicine January 2025, jnumed.124.268638; DOI: https://doi.org/10.2967/jnumed.124.268638 ...

When one looks at the feedback loops created by autoreceptors on the presynaptic membrane ... of neurotransmitter that is made available to receptors on the cell membrane also binds to ...

A team of researchers from the University of Massachusetts Amherst is the first to show how proteins called "chaperones" are ...

To do this, the synaptic vesicle must dock at the membrane of the presynaptic neuron and dump its content into the synapse, where it moves to particular receptors on the postsynaptic neuron.

This fundamental work provides evidence that glutamate and GABA are released from different synaptic vesicles at supramammillary axon terminals onto granule cells of the dentate gyrus. The study uses ...

This is important given that Rimonabant, a weight-loss drug that targeted cannabinoid receptors in the central ... in mesoaccumbens postsynaptic but not presynaptic neurons prevents diet-induced ...