The pyruvate dehydrogenase complex consists of many different enzymes (marked in different colours). Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted ...

Saol Therapeutics, a privately held, clinical-stage pharmaceutical company, today announced the submission of a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) for approval ...

Gene mutations in the mitochondrial Pyruvate Dehydrogenase Complex (PDC) lead to congenital PDCD. PDC is inhibited by pyruvate dehydrogenase kinases (PDK), that may be over-expressed in PDCD.