Certain forms of histone methylation cause local formation of heterochromatin, which is readily reversible, whereas DNA methylation leads to stable long-term repression. It has recently become ...

resulting in histone H3K9me3-mediated heterochromatin. They demonstrated that ZNF512 and ZNF512B from different species can specifically target pericentric heterochromatin regions in other ...

it is also retained in the absence of the histone methyltransferase, Suv39, in female mouse cells, which abolished H3–Lys9 methylation in constitutive but not in facultative heterochromatin ...

During replication, the double-stranded DNA strand unwinds from around the histone ... of compacted heterochromatin and make the DNA molecule accessible to the deposition of methylation," explains ...

(5) The PIWI-piRNA complexes can enter the nucleus and regulate gene transcription through epigenetic mechanisms including heterochromatin formation and DNA methylation in the promoter region of ...