Hepatitis B virus (HBV) has a narrow host range, mainly infecting hominoids. A new study reveals the structural differences in the liver cell receptor (NTCP) between humans and monkeys, explaining why ...
The figure shows how the hepatitis B virus (HBV) infection is restricted by two sites on the macaque liver cell receptor NTCP. (a) Cryo-electron microscopic structure of macaque NTCP (cyan)-bile ...
Patients with chronic hepatitis B present a profound defect of hepatitis B virus (HBV)-specific T-cell immunity. Antiviral treatment in chronic hepatitis B patients suppresses HBV replication but ...
Hepatitis B virus (HBV) infection is a leading cause of chronic liver diseases, that spreads among individuals through blood or body fluids. According ...
probably due to pressure from HBV. Such molecular evolution driven to escape virus infection has been reported for other virus receptors." Further lab experiments and simulations revealed that an ...