Conditional gene targeting based on excision or inversion of loxP-flanked DNA segments by Cre recombinase is a powerful technology for the analysis of gene function, but unexpected expression ...
The investigator will submit a request form through iLab with a detailed gene targeting strategy and proven screening protocol. An account and IACUC number must be provided at this time. The ES cell ...
Gene therapy in the central nervous system ... Here we provide evidence for a novel, noninvasive approach for targeting potential therapeutic factors to the CNS. Genetically-modified hematopoietic ...
Investigator submits a targeting strategy and demonstrates a proven screening protocol ... Investigator will breed chimera and confirm germline transmission of gene.
In a single IV injection, a gene therapy targeting cBIN1 can reverse the effects of heart failure and restore heart function in a large animal model. The therapy increases the amount of blood the ...
vectors for gene therapies targeting neurological diseases. Dyno and Roche previously announced a research collaboration and license agreement for neurological diseases and liver-directed ...