Nature5 年
Bortezomib improves arthritis in a mouse model
assessed the efficacy of the proteasome inhibitor bortezomib on collagen-induced arthritis (CIA), a mouse model of rheumatoid arthritis. Two doses of type II collagen, administered 2 weeks apart ...
Nature5 年
Anti-osteopontin monoclonal antibody improves and prevents arthritis in a mouse model
examined the efficacy of two novel anti-osteopontin monoclonal antibodies (mAbs; 23C3 and F8E11) in the treatment of murine collagen-induced arthritis (CIA), an animal model of human RA.